Retrospective evaluation of patients with Kawasaki disease Kawasaki hastalığı tanılı olgularımızın geriye yönelik değerlendirilmesi
Cocuk Enfeksiyon Dergisi, cilt.14, sa.2, 2020 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 14 Sayı: 2
- Basım Tarihi: 2020
- Doi Numarası: 10.5578/ced.202022
- Dergi Adı: Cocuk Enfeksiyon Dergisi
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
- Anahtar Kelimeler: Kawasaki disease, Mucocutaneous lymph node syndrome, Turkey
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Kawasaki disease (KD) is an acute febrile disease of the child-hood characterized by vasculitis. The disease is thought to be due to the abnormal inflammatory response caused by various infectious agents in genetically predisposed individuals. It is known that the disease can be seen in all ethnic groups but it is more common in Asian populations. Al-though there is no recorded data on the incidence of KD in our country, it cannot be considered as a rare disease. Material and Methods: In this study, demographic characteristics, clinical and laboratory findings, treatment processes, and if any, complications of the cases diagnosed as KD during the last 5 years were retrospectively evaluated. Results: In the study, 24 patients were enrolled; 13 were males (54.2%), 11 were females (45.8%), and the median age was 25 months (range 8 to 122 months). Patients were diagnosed most frequently in spring (58.3%) and winter (29.2%). The duration of hospitalization was 11.52 ± 4.4 (range 4-23) days. The most common symptoms accompanying fever were oropharyngeal lesions (79.2-19 of patients). It was seen that 16 (66.7%) of the patients were diagnosed as complete KD and 8 (33.3%) of them were diagnosed as incomplete KD. Eighteen (75%) patients re-sponded to intravenous immunoglobulin (IVIG) at the first dose, 6 (25%) patients had fever after 36 hours of IVIG treatment, and thus were given additional IVIG treatment and 1 (4.2%) patient did not respond to IVIG treatments and steroid was started. Eight (33.3%) of the patients were found to have cardiac involvement and 4 of them were still under anti-aggregant treatment. Conclusion: Increasing awareness of incomplete forms of KD and defin-ing incomplete KD diagnostic laboratory criteria have led to an increase in the incidence of KD in recent years. It is useful to keep the defined laboratory criteria in mind in order not to overlook the incomplete forms of the disease where classical KD clinical criteria are not met.