The relationship between serum ferritin levels and disease activity in systemic lupus erythematosus
Scandinavian Journal of Rheumatology, cilt.32, sa.4, ss.225-228, 2003 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 4
- Basım Tarihi: 2003
- Doi Numarası: 10.1080/03009740310003712
- Dergi Adı: Scandinavian Journal of Rheumatology
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.225-228
- Anahtar Kelimeler: systemic lupus erythematosus, serum ferritin, SLEDAI, acute phase response
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: The aim of this study is to investigate the relationship between serum ferritin levels and disease activity in patients with systemic lupus erythematosus (SLE). Methods: Serum ferritin levels of 72 SLE patients were measured. The SLE patients were subdivided into two groups according to SLE disease activity index (SLEDAI) as ≤ 10 and ≥ 11. The results were compared with 31 patients with rheumatoid arthritis (RA). 36 patients among 72 with SLE were evaluated before and after treatment. Results: Serum levels of ferritin in SLE patients were higher than RA patients (p < 0,001). There was a significant difference in ferritin levels before and after treatment. The levels of ferritin in SLE were positively correlated with SLEDAI scores. Patients with SLEDAI scores ≥ 11 had significantly higher serum ferritin levels. Conclusion: Serum ferritin levels may be a useful marker of disease activity in SLE patients.