Stereotactic radiosurgery in pituitary adenomas: A single center experience Hipofiz adenomlari·nda stereotaktik radyocerrahi: Tek merkez deneyimi
UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi, cilt.22, sa.4, ss.255-260, 2012 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 22 Sayı: 4
- Basım Tarihi: 2012
- Doi Numarası: 10.4999/uhod.11077
- Dergi Adı: UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.255-260
- Anahtar Kelimeler: Pituitary adenoma, Stereotactic radiosurgery, Growth hormone
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
The aim of this study was to evaluate the efficiency of stereotactic radiosurgery (SRS) in the management of pituitary adenomas. Between June 1998 and July 2011, 57 patients with pituitary adenomas were treated using SRS at our department. All patients underwent high-precision single dose SRS using a linear accelerator with 6-MV photons. Median follow-up time was 31.5 (3-92) months. Median age was 40 years (range: 19-57 years). Radiological tumor growth control was achieved in 48 patients (84.2%) (a decrease in tumor size in 25 patients and no change in tumor size in 23 patients). 13 patients with functioning adenomas had available biochemical follow-up and biochemical complete response was achieved in 8 (61.5%) of these 13 patients. Treatment of pituitary adenomas using LINAC-based single dose SRS is safe and effective in improving local tumor and biochemical control.