Comparison of Combination Therapy of Adenosine and Nitroprusside with Adenosine Alone in the Treatment of Angiographic No-Reflow Phenomenon


BARÇIN C., Denktas A. E., Lennon R. J., Hammes L., Higano S. T., Holmes Jr. D. R., ...Daha Fazla

Catheterization and Cardiovascular Interventions, cilt.61, sa.4, ss.484-491, 2004 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 4
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1002/ccd.20010
  • Dergi Adı: Catheterization and Cardiovascular Interventions
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.484-491
  • Anahtar Kelimeler: coronary, adenosine, coronary blood flow, percutaneous coronary intervention
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

We sought to compare the combination therapy of adenosine and nitroprusside in no-reflow phenomenon during percutaneous coronary intervention. Improvement in coronary flow from no-reflow to postdrug state was evaluated. Patients who received adenosine (n = 21) were compared to ones who received the combination of adenosine and nitroprusside (n = 20) for treatment. Improvement of TIMI flow grades was higher in the group that received combined therapy (1.5 ± 1.0 vs. 0.8 ± 0.6; P < 0.05). Combination therapy of adenosine and nitroprusside is safe and provides better improvement in coronary flow compared to intracoronary adenosine alone in case of impaired flow during coronary interventions. © 2004 Wiley-Liss, Inc.