Evaluation of retinal vascular structure after epiretinal membrane surgery by optical coherence tomography angiography
International Ophthalmology, cilt.41, sa.2, ss.621-627, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 41 Sayı: 2
- Basım Tarihi: 2021
- Doi Numarası: 10.1007/s10792-020-01617-9
- Dergi Adı: International Ophthalmology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
- Sayfa Sayıları: ss.621-627
- Anahtar Kelimeler: Epiretinal membrane, FAZ area, Optical coherence tomography angiography, Vessel density
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose: To evaluate the retinal vascular structure before and after the epiretinal membrane (ERM) surgery by optical coherence tomography angiography (OCTA). Methods: Twenty-two eyes with ERM (study eyes) had been evaluated by OCTA for superficial capillary plexus (SCP) and deep capillary plexus (DCP) vessel density (VD) at foveal and parafoveal regions and foveal avascular zone (FAZ) before and after ERM removal surgery. Twenty-two fellow eyes were selected as control group. Results: Preoperative VD of SCP and DCP were significantly lower in ERM eyes than in controls in both foveal and parafoveal areas (p < 0.05, for all). The difference regressed in SCP (fovea: 18.04 ± 3.1 vs 19.98 ± 18 p = 0.002 and parafovea: 47.33 ± 3.54 vs 49.71 ± 28 p = 0.001), but persisted in DCP (fovea: 17.25 ± 3.52 vs 17.57 ± 4.01 p = 0.856 and parafovea: 50.12 ± 4.35 vs 50.93 ± 3.24 p = 0.791) in study eyes, postoperatively. Superficial and deep FAZ areas were significantly smaller in study eyes than controls. Postoperatively, superficial FAZ area enlarged (0.288 ± 0.10 vs 0.307 ± 0.08 p = 0.012), whereas deep FAZ area did not (0.324 ± 0.09 vs 0.338 ± 0.07 p = 0.435). FAZ area was correlated with the best-corrected visual acuity in ERM eyes. Conclusion: Vascular damage in SCP and DCP was demonstrated by OCTA in eyes with ERM. ERM removal surgery mainly improves superficial changes caused by ERM. Changes in deep retinal flow may be associated with visual outcomes after ERM removal surgery.