Aspirin in cardiovascular prevention: Does the approach differ by gender? Kardiyovasküler korumada aspirin: Cinsiyete göre farkli bir yaklaşim var mi?
Anadolu Kardiyoloji Dergisi, cilt.7, sa.SUPPL. 2, ss.2-4, 2007 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 7 Sayı: SUPPL. 2
- Basım Tarihi: 2007
- Dergi Adı: Anadolu Kardiyoloji Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.2-4
- Anahtar Kelimeler: Aspirin, Cardiovascular disease, Prevention, Sex
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Although aspirin is effective in the treatment of acute coronary syndrome and in the secondary prevention of cardiovascular disease among both men and women, its use in primary prevention remains controversial. The gender-specific meta-analysis demonstrates that the specific types of benefit of aspirin therapy differ between women and men in primary prevention. For primary prevention of cardiovascular disease in women, aspirin therapy significantly reduced the risk of the composite of cardiovascular events primarily by its effect on reducing the risk of stroke In contrast, in men; aspirin therapy significantly reduced the risk of the composite of cardiovascular events predominantly by reducing the risk of myocardial infarction. The reasons for any sex-based differences in the efficacy of aspirin for primary prevention are unclear and require further exploration.