Heterozygous methylenetetrahydrofolate reductase 677C-T gene mutation with mild hyperhomocysteinemia associated with intrauterine iliofemoral artery thrombosis


ALİOĞLU B., Ozyurek E., Tarcan A., Atac F. B., Gurakan B., ÖZBEK N. Y.

Blood Coagulation and Fibrinolysis, cilt.17, sa.6, ss.495-498, 2006 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 6
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1097/01.mbc.0000240925.03425.c0
  • Dergi Adı: Blood Coagulation and Fibrinolysis
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.495-498
  • Anahtar Kelimeler: intrauterine thrombosis, methylenetetrahydrofolate reductase 677C-T gene mutation, mild hyperhomocyteinemia
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Neonatal thrombosis is a serious event that can cause mortality or severe morbidity. Newborn-related factors, including genetic prothrombotic risk factors, may affect the occurrence of neonatal thrombosis. In this report, a case of intrauterine iliofemoral arterial thrombosis associated with mild hyperhomocysteinemia caused by methylenetetrahydrofolate reductase 677C-T gene mutation is presented. We suggest that methylenetetrahydrofolate reductase gene mutation might be investigated in neonates and their families presenting with thromboembolic disease. © 2006 Lippincott Williams & Wilkins.