A rare tumor in the sellar region: ganglioglioma, a case report and a general overview
Child's Nervous System, cilt.39, sa.12, ss.3621-3626, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 39 Sayı: 12
- Basım Tarihi: 2023
- Doi Numarası: 10.1007/s00381-023-06073-1
- Dergi Adı: Child's Nervous System
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, MEDLINE
- Sayfa Sayıları: ss.3621-3626
- Anahtar Kelimeler: Pediatric neurosurgery, Endoscopic skull base surgery, Childhood brain tumor, Glioneuronal neoplasm
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Gangliogliomas are rare mixed neuronal-glial tumors of the central nervous system, accounting for less than 2% of intracranial tumors. Case description: This report presents a rare case of ganglioglioma in the sellar region of a 3-year-old and 5-month-old pediatric patient. The patient underwent surgical intervention initially through a transnasal transsphenoidal approach and subsequently through a transcranial pterional craniotomy approach. Subsequently, radiotherapy and chemotherapy were administered for residual tumor tissue. The purpose of this report is to highlight the presence of ganglioglioma as a distinct diagnosis in sellar region tumors, discuss the surgical, radiotherapy, and/or chemotherapy treatment options for sellar region gangliogliomas based on the literature, and contribute the patient’s follow-up and treatment outcomes to the existing literature. Conclusion: Complete tumor resection may not be feasible in sellar region gangliogliomas, especially in pediatric cases, due to endocrinological and vision-related complications. In cases where complete resection is not possible, radiotherapy and/or chemotherapy may be considered. However, the optimal treatment approach has not yet been established, and further research is needed.