Reversal of Oral Vitamin K Antagonists Using Prothrombin Complex Concentration Prior to IV tPA Administration
Neurology India, cilt.70, sa.3, ss.1238-1239, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 70 Sayı: 3
- Basım Tarihi: 2022
- Doi Numarası: 10.4103/0028-3886.349620
- Dergi Adı: Neurology India
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.1238-1239
- Anahtar Kelimeler: Acute stroke treatment, international normalized ratio (INR), intravenous tissue plasminogen activator (tPA), prothrombin complex concentrate (PCC), warfarin iv thrombolytic
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Herein, we report two acute ischemic stroke cases that we used prothrombin complex to reverse the effects of warfarin in order to apply intravenous thrombolytic treatment. To the best of our knowledge, there are only limited amount of cases that prothrombin complex concentrates were applied prior to intravenous thrombolytic treatment administration. As one of the biggest acute stroke clinics in our country, we aim to open a discussion for this treatment to be fully researched and understood.