Evaluating the effect of being away from work environment on oxidative stress levels with dynamic thiol-disulfide homeostasis among anesthesiology professionals Anestezi Çalışanlarında çalışma ortamından uzaklaşmanın oksidatif stres düzeylerine etkisinin dinamik tiyol disülfit dengesi ile değerlendirilmesi
Anestezi Dergisi, cilt.28, sa.2, ss.80-84, 2020 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 28 Sayı: 2
- Basım Tarihi: 2020
- Doi Numarası: 10.5222/jarss.2020.05925
- Dergi Adı: Anestezi Dergisi
- Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, Central & Eastern European Academic Source (CEEAS), EMBASE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.80-84
- Anahtar Kelimeler: Anesthesiology, Inhalation anesthetics, Oxidative stress, Sulfhydryl compounds, Waste products
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Exposure to anesthetic gases and occupational stress lead to increased levels of oxidative stress in anesthesiology professionals. Our study aims to investigate the effects of being away from anesthetic practice on oxidative stress with thiol-disulfide balance in anesthesiology professionals. Method: The study included a total of 29 volunteers among anesthesiologists, residents and technicians working in anesthesiology practice and planning to take a leave lasting at least for a week. Demographic data, working times and duties of them were recorded. Blood samples were taken from the participants on the day before they went on leave and on the day they returned, to study dynamic thiol-disulfide homeostasis. Increased native and total thiol levels and decreased disulfide levels after returning were evaluated as a decrease in oxidative stress. The data were assessed with a t-test, a one-way analysis of variance, a paired t-test; and p<0.05 was considered statistically significant. Results: The mean leave was 10.7±3 days. Anesthesiologists had a higher mean age, while residents had a shorter working time (p<0.001). Other demographic data and pre-leave native thiol, total thiol and disulfide values were similar in three groups. A post-leave decrease in oxidative stress was noted among specialists and residents, whereas no significant change was observed in the technicians. Conclusion: Based on the fact that decreasing levels of oxidative stress after 10-day leave, we believe that distancing the anesthesiologists from the work environment at specific intervals would be beneficial in terms of employee health.