Cold-induced Vascular Changes in the Macula, Optic Disc and Choroid in Children with Raynaud’s Phenomena
Ocular Immunology and Inflammation, cilt.31, sa.2, ss.277-285, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 2
- Basım Tarihi: 2023
- Doi Numarası: 10.1080/09273948.2022.2026411
- Dergi Adı: Ocular Immunology and Inflammation
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.277-285
- Anahtar Kelimeler: Children, choroid, Raynaud's phenomenon, retina, optik coherence tomography angiography
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: To investigate changes in retinal and choroidal vessels in children with primary and secondary raynaud’s phenomena(RP). Methods: Measurements were performed by optic coherence tomography angiography before as well as during and 10 minutes after the immersion of one hand in ice water. Results: Primary RP patients exhibited enlargement of the foveal avascular region and decrease in vessel density in the parafoveal superficial capillary plexus (SCP) during cold exposure, but values returned to normal when the hands were removed from the cold water. In children with secondary RP, there were decreases in choroidal thickness and vessel density in the SCP and radial peripapillary capillary plexus (RPCP) during cold exposure. Changes in choroid and peripapillary RPCP were still significant 10 minutes after removal from cold water. Conclusion: Ocular arteriolar vasospasm seems to be more pronounced in patients with secondary RP, particularly in the choroid and the peripapillary area of the RPCP. Clinical Trial Registration Number and Date: Decision number: 76/1315 - 10.03.2021.