High levels of serum uric acid impair development of coronary collaterals in patients with acute coronary syndrome
Angiology, cilt.63, sa.6, ss.472-475, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 63 Sayı: 6
- Basım Tarihi: 2012
- Doi Numarası: 10.1177/0003319711422433
- Dergi Adı: Angiology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.472-475
- Anahtar Kelimeler: serum uric acid, coronary collateral vessels, acute coronary syndrome
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
We evaluated the association of serum uric acid (SUA) level and development of coronary collateral vessels (CCVs) in patients with acute coronary syndrome (ACS). Patients (n = 224) with ACS were included in the study. Coronary collateral vessels were graded according to the Rentrop scoring system. Rentrop grade 0 was accepted as absence of CCV (group 1; n = 117) and Rentrop grade ≥1 was accepted as presence of CCV (group 2; n = 107). Rentrop 0-1 (poor CCV) were determined in 167 patients and Rentrop 2-3 (good CCV) were determined in 57 patients. Both presence of CCV (P <.001) and development of good CCV (P =.003) were significantly associated with low levels of SUA. We suggest that high levels of SUA affect the CCV development negatively in nondiabetic and nonhypertensive patients with ACS. © The Author(s) 2012.