A case of propylthiouracil-induced antineutrophilic cytoplasmic antibody-positive vasculitis successfully treated with radioactive iodine
Reumatismo, cilt.65, sa.3, ss.131-133, 2013 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 65 Sayı: 3
- Basım Tarihi: 2013
- Doi Numarası: 10.4081/reumatismo.2013.131
- Dergi Adı: Reumatismo
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.131-133
- Anahtar Kelimeler: Propylthiouracil, Antineutrophilic cytoplasmic antibody (ANCA), Radioactive iodine
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Antineutrophilic cytoplasmic antibody (ANCA) associated vasculitis is one of the rare complications of propyl-thiouracil treatment. Having a variable clinical spectrum, it may be presented with both skin limited vasculitis and life-threatening systemic vasculitis. In this study, we present a case that developed ANCA-positive vascu-litis with skin and kidney involvement (hematuria and proteinuria) six months after propylthiouracil treatment was initiated for toxic nodular goiter. Proteinuria recovered dramatically subsequent to radioactive iodine treat-ment following ceasing the drug.