Is68Ga-Prostate-Specific Membrane Antigen PET/CT Superior than18F-FDG PET/CT for Evaluation of Metastatic Osteosarcoma?
Clinical Nuclear Medicine, cilt.46, sa.4, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 46 Sayı: 4
- Basım Tarihi: 2021
- Doi Numarası: 10.1097/rlu.0000000000003320
- Dergi Adı: Clinical Nuclear Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Anahtar Kelimeler: F-18-FDG, Ga-68-PSMA, osteosarcoma, PET/CT, PSMA
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
We present the case of a 75-year-old man with osteosarcoma of the sternum in whom 68Ga-prostate-specific membrane antigen (PSMA) PET/CT showed high radiotracer activity in the primary tumor and metastatic lesions than 18F-FDG PET/CT. The present case shows that 68Ga-PSMA PET/CT is very useful for staging of osteosarcoma due to in vivo expression of PSMA. 68Ga-PSMA PET/CT can have potential effects on prognosis and in response assessment following treatment in osteosarcoma. The use of PSMA-Targeted radioligand treatments may be beneficial especially in metastatic chemorefractory osteosarcoma.