Effects of fentanyl and propofol anaesthesia on somatosensory evoked potentials
Turk Anesteziyoloji ve Reanimasyon, cilt.20, sa.3, ss.185-188, 1992 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 3
- Basım Tarihi: 1992
- Dergi Adı: Turk Anesteziyoloji ve Reanimasyon
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.185-188
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Somatosensory evoked potentials are known as the potentials evoked by stimulation of peripheral nerve and recorded from different points on afferent sensory pathways. They are used frequently for monitoring specific neural pathways at risky patients during surgery. Effects of fentanyl and propofol anaesthesia on median nerve SEP's were investigated in 14 patients undergoing hypothermic cardiac surgery. The study was performed in two groups each consisting of 7 patients. In the first group induction was made by 35 μ/kg fentanyl and 0.5 mg/kg diazepam and in the other by 20 μ/kg fentanyl and 10 mg/kg/h propofol infusion. Pancuronium bromide 0.1 mg/kg was used as muscle relaxant, fentanyl for the maintenance in the first group and propofol in the second one. SEP records were assessed at preinduction (control), 20 minutes after the induction, during hypothermia (30°C) and after cardiopulmonary bypass. Data were compared with the preinduction values. In both groups peak latencies of N13 and N19 showed significant differences (p _ 0.05). During hypothermia latencies of N13, N19 (p _ 0.01) and CCT (p _ 0.05) increased significantly. Where as CCT showed no significant difference at postinduction. After the induction the amplitudes showed depression in both groups but the depression in the fentanyl group was more significant. During hypothermia there was no change of amplitude values. In conclusion, it has been observed that both drugs effect SEP latencies and amplitudes especially during hypothermia where the CCT values showed a significant increased.