Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome That Develops After Hysterectomy Surgery


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Çeti̇N Arslan H., CAN E., Türkmen E.

Journal of Clinical Obstetrics and Gynecology, cilt.33, sa.4, ss.245-248, 2023 (ESCI, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 4
  • Basım Tarihi: 2023
  • Doi Numarası: 10.5336/jcog.2022-94674
  • Dergi Adı: Journal of Clinical Obstetrics and Gynecology
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, Central & Eastern European Academic Source (CEEAS), Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.245-248
  • Anahtar Kelimeler: DRESS syndrome, drug hypersensitivity, eosinophilia, fever
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

DRESS syndrome, “drug reaction with eosinophilia and systemic symptoms,” is a hypersensitivity reaction that can lead to severe organ dysfunction and mortality. Increased reactive metabolites are thought to cause an immunological response due to inadequate detoxification of the responsible drug. The drugs with which the reaction is most frequently observed are anticonvulsants and sulfonamides. It can be fatal with the reuse of some groups of drugs. Early diagnosis of the disease and discontinuation of the responsible drug in the early period of the reaction is essential. Systemic steroids are used in treatment, and intravenous immunoglobulin is used when necessary. We have presented a 43-year-old female patient diagnosed with DRESS syndrome who was using nitrofurantoin because of a Double J catheter.