Effect of estimated glomerular filtration rate on periprocedural myocardial infarction in patients undergoing elective percutaneous coronary intervention

Vatankulu M. A., MURAT S. N., Demircelik B., Turfan M., Sonmez O., DURAN M., ...Daha Fazla

Renal Failure, cilt.35, sa.7, ss.931-935, 2013 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 7
  • Basım Tarihi: 2013
  • Doi Numarası: 10.3109/0886022x.2013.808132
  • Dergi Adı: Renal Failure
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.931-935
  • Anahtar Kelimeler: Glomerular filtration rate, periprocedural myocardial infarction, renal insufficiency, stable angina pectoris
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Backgrounds: Little is known about the effect of the estimated glomerular filtration rate (eGFR) on the periprocedural myocardial infarction (PMI). The aim of this study was to determine an eGFR value that is related with PMI development in patients with stable angina undergoing elective percutaneous coronary intervention (PCI). Method: A retrospective analysis was conducted of 257 consecutive PCI patients with stable angina pectoris. The patients were divided into three groups according to eGFR: Group 1: eGFRgt;0L/min/1.73, Group 2: eGFR60-89L/min/1.73, and Group 3: eGFR30-59L/min/1.73. Cardiac biomarkers were measured before, at 8, and at 24 after the procedure. Results: Periprocedural myocardial infarction occurred in 19% of the study patients. The frequency of PMI was 13.8% in group 1, 15.2% in group 2, and 35% in group 3 (p0.002). There was an inverse relationship with increasing cardiac biomarkers and decreasing eGFR values. Multiple regression analysis showed that an eGFR value between 30 and 59L/min/1.73 was an independent variable that significantly affected PMI development after PCI. Conclusions: An estimated glomerular filtration rate between 30 and 59L/min/1.73m is a predictor of developing PMI after elective PCI in patients with stable angina pectoris. © 2013 Informa Healthcare USA, Inc. All rights reserved: reproduction in whole or part not permitted.