Parry-Romberg syndrome in association with anti-dsDNA antibodies: A case report


GÖNÜL M., Dogan B., İZCİ Y., Varol G.

Journal of the European Academy of Dermatology and Venereology, cilt.19, sa.6, ss.740-742, 2005 (SCI-Expanded, Scopus)

Özet

Parry-Romberg syndrome (PRS) is a rare and puzzling disorder that is characterized by progressive hemifacial atrophy. It involves mainly some or all tissues of one side of the face. A case of 21-year-old Caucasian man with hemifacial atrophy in the right facial region is reported. Serological studies with anti-single-stranded DNA (anti-ssDNA), anti-double-stranded DNA (anti-dsDNA), anticentromere (ACA) and antinuclear (ANA) antibodies were done. Anti-dsDNA antibodies was found positive, but the others were negative. Rheumatoid factor (RF) was also negative. Since PRS is rare and its association with anti-dsDNA antibodies was not reported before, this case appears to be the first report. © 2005 European Academy of Dermatology and Venereology.