Cardiac Function in Chronic Obstructive Pulmonary Disease: Role of MAPSE

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Guler Y., Akgün H., Halil U. S., Kılıç Ş., Acar G., Azaklı D., ...Daha Fazla

Eastern Journal of Medicine, cilt.30, sa.4, ss.501-507, 2025 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 4
  • Basım Tarihi: 2025
  • Doi Numarası: 10.5505/ejm.2025.37236
  • Dergi Adı: Eastern Journal of Medicine
  • Derginin Tarandığı İndeksler: Scopus, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.501-507
  • Anahtar Kelimeler: Chronic obstructive pulmonary disease, diastolic dysfunction, left ventricular function, MAPSE, systolic dysfunction
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

This study aims to investigate the role of mitral annular plane systolic excursion (MAPSE) in evaluating left ventricular function in patients with chronic obstructive pulmonary disease (COPD). This study included 53 COPD patients and 51 healthy controls. All participants underwent echocardiographic evaluation, including tissue Doppler imaging. Lateral MAPSE was measured via M-mode in the apical four-chamber view. The mean age of the study population was 63.5 ± 8.8 years, with 69.2% male. No significant differences were observed between the COPD (n=53) and control (n=51) groups regarding age, sex, heart rate, blood pressure, comorbidities, or laboratory findings, though smoking was more prevalent in the COPD group. Pulmonary function tests showed significantly lower FEV1 and FEV1/FVC in COPD patients (p<0.001). Conventional echocardiographic parameters including left ventricular dimensions and ejection fraction were similar between groups. However, the COPD group exhibited higher LAVi and e/E′ ratios, lower E′ velocities, and impaired right ventricular function indicated by reduced TAPSE and Sm-RV and elevated PAPs (all p<0.001). Importantly, MAPSE values were significantly decreased in COPD patients, reflecting impaired longitudinal left ventricular function [11.3 (9.6–13.8) vs. 13.7 (13.4–15.2), p<0.001]. Reduced MAPSE in COPD patients may indicate early LV systolic dysfunction. MAPSE is a simple and reliable parameter that may aid in the early detection of cardiac involvement in COPD.