Partial exchange transfusion for neonatal polycythemia
Turk Pediatri Arsivi, cilt.47, sa.1, ss.23-28, 2012 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 47 Sayı: 1
- Basım Tarihi: 2012
- Doi Numarası: 10.4274/tpa.588
- Dergi Adı: Turk Pediatri Arsivi
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.23-28
- Anahtar Kelimeler: Exchange transfusion, newborn, polycythemia
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: The aim of this study was to investigate the short term effects of partial exchange transfusion on the morbidity of preterm and term polycythemic neonates. Material and Method: Late preterm and term infants with polycythemia hospitalized in Zeynep Kamil Maternity and Children's Training Hospital Neonatal Intensive Care Unit from January 2009 to May 2010 were evaluated retrospectively. Results: One hundred-sixty-three of 16.000 infants who were born during the study period were hospitalized with a diagnosis of polycythemia. The incidence of polycythemia was 1%. Late preterm polycythemic (n=68/163; 41.7%) patients were divided into two groups as symptomatic (n=23/163; 14.1%) and asymptomatic (n=45/163; 27.6%) infants. Term polycythemic (n=95/163; 58.3%) patients were divided into two groups as symptomatic (n=21/163; 12.9%) and asymptomatic (n=74/163; 45.4%) infants. Partial exchange transfusion (PET) was performed in 102 patients. Of these infants, 18/102 (17.7%) were symptomatic late preterm, 23/102 (22.6%) were asymptomatic late preterm, 14/102 (13.7%) were symptomatic term and 47/102 (46%) were asymptomatic term infants. The number of patients who were treated medically (hydration) was 61. Of these patients 5/61 (8.2%) were symptomatic late preterm, 22/61 (36%) were asymptomatic late preterm, 7/61 (11.5%) were symptomatic term and 27/61 (44.3%) were asymptomatic term patients. Duration of hospitalization in the term symptomatic group and time to reach full enteral feeding in the asymptomatic term group were longer in patients in whom PET was performed. (p<0.05). There were four patients (2 preterm, 2 term) who developed NEC following PET. Conclusions: Our results showed that PET influences duration of hospitalization and time to reach full enteral feeding and increases the risk of NEC in asymptomatic patients. We believe that more studies should be performed to determine the indications of PET in asymptomatic infants.