The panacea for cardiovascular diseases: The role of statins in the management of heart failure


Celik T., Iyisoy A., YÜKSEL U. Ç., Isik E.

International Journal of Cardiology, cilt.129, sa.3, ss.422-423, 2008 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 129 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.ijcard.2007.06.045
  • Dergi Adı: International Journal of Cardiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.422-423
  • Anahtar Kelimeler: chronic heart failure, statins, cardiovascular mortality
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

The data obtained from retrospective studies have indicated that patients with chronic heart failure (CHF) on statin treatment have good cardiovascular outcomes, in both ischemic and nonischemic dilated cardiomyopathy. There is an ongoing debate about whether the effects of statins on ubiquinone and cholesterol levels might have a negative impact in patients with CHF. We believe that 3 large scale ongoing randomized clinical trials (the GISSI-HF, CORONA and UNIVERSE) will come to end the debate over the safety and efficacy of statin treatment in patients with CHF. © 2007 Elsevier Ireland Ltd. All rights reserved.