The association of allergic rhinitis severity with neutrophil–lymphocyte and platelet–lymphocyte ratio in adults
European Archives of Oto-Rhino-Laryngology, cilt.276, sa.12, ss.3383-3388, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 276 Sayı: 12
- Basım Tarihi: 2019
- Doi Numarası: 10.1007/s00405-019-05640-0
- Dergi Adı: European Archives of Oto-Rhino-Laryngology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.3383-3388
- Anahtar Kelimeler: Allergic rhinitis, Neutrophil-lymphocyte ratio, Platelet-lymphocyte ratio
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: To investigate the association of allergic rhinitis (AR) severity with neutrophil–lymphocyte and platelet–lymphocyte ratios in adult patients. Methods: The study design was prospective observational study and the study included 209 AR patients and 243 healthy individuals. The patient group comprised 38.2% males with a mean age of 31.8 years. All patients who were diagnosed with persistent AR were included. The healthy control group comprised 52.7% males with a mean age of 32.3 years. The blood examination results of patients and healthy individuals were compared in terms of neutrophil–lymphocyte and platelet–lymphocyte ratios. The values were further compared within the patient group, according to AR severity. Results: The neutrophil–lymphocyte ratio was 1.70 ± 0.65 in the healthy group and 2.02 ± 1.24 in the patient group. The platelet–lymphocyte ratio result was 100.85 ± 25.33 in the healthy group and 120.67 ± 40.59 in the patient group. When we compared the neutrophil–lymphocyte and platelet–lymphocyte ratios between the groups, we found statistically significant differences in both ratios (p = 0.003, p = 0.000, respectively). Both the neutrophil–lymphocyte and the platelet–lymphocyte ratios were higher in patients with moderate–severe AR. Conclusion: Both neutrophil–lymphocyte and platelet–lymphocyte ratios are useful markers for diagnosis of persistent AR. Specialists may benefit from these markers to assess the severity of the disease at the beginning of the diagnostic process.