A Clinical Investigation on ADHD-Traits in Childhood Celiac Disease


Efe A., Tok A.

Journal of Attention Disorders, cilt.27, sa.4, ss.381-393, 2023 (SCI-Expanded, SSCI, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 4
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1177/10870547221149195
  • Dergi Adı: Journal of Attention Disorders
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, CINAHL, MEDLINE, Psycinfo
  • Sayfa Sayıları: ss.381-393
  • Anahtar Kelimeler: ADHD, celiac disease, CPRS-48, SDQ, inattention, learning problems, prosocial behaviors, pediatrics
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: There are no definitive results about either the presence of exact comorbidity between celiac disease (CD) and attention-deficit/hyperactivity disorders (ADHD) or etiology. We intend to screen ADHD-related cognitive and behavioral traits in children with biopsy-proven CD and investigate the possible association of these traits with certain vitamin levels, body-mass index, and gluten-free diet (GFD) compliance. Method: A total of 85 children with biopsy-proven CD (the ages of 8–18 years) were compared with age and sex-matched 72 healthy controls in terms of demographics, psychiatric symptoms, certain vitamin levels, and anthropometric measurements. Results: ADHD-like cognitive issues, such as inattention and learning difficulties, as well as psychosomatic symptoms and poor prosocial behavior, were all associated with GFD noncompliance in childhood CD. Conclusion: Untreated CD may predispose to ADHD-resembling symptoms. Physicians should be aware of the probability of ADHD misdiagnosing due to ADHD-resembling cognitive and behavioral traits in untreated CD.