Estimated glomerular filtration rate may not be correlated with the grade of coronary collateral circulation in patients with chronic total occlusion


ÜREYEN Ç. M., Coşansu K., VURAL M. G., Şahin S. E.

Cardiovascular journal of Africa, cilt.36, sa.3, ss.261-266, 2025 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 3
  • Basım Tarihi: 2025
  • Doi Numarası: 10.5830/cvja-2025-042
  • Dergi Adı: Cardiovascular journal of Africa
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.261-266
  • Anahtar Kelimeler: chronic total occlusion, coronary collateral circulation, estimated glomerular filtration rate
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

BACKGROUND AND OBJECTIVE: The impact of baseline renal function on coronary collateral circulation (CCC) development remains debated. This study aimed to assess the relationship between CCC grade and estimated glomerular filtration rate (eGFR) in patients undergoing percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). METHODS: A total of 203 eligible patients from 212 consecutive CTO procedures over 18 months were analysed. Patients were classified based on an eGFR cut-off of 60 ml/min/1.73m2 or CCC grading (Rentrop/Werner), and median eGFR levels were compared. RESULTS: No significant correlation was found between baseline eGFR and CCC grade, whether using the eGFR cut-off (p = 0.174 Rentrop, p = 0.867 Werner) or median eGFR classification (p = 0.692 Rentrop, p = 0.271 Werner). CONCLUSION: Baseline renal function may not have a direct correlation with CCC grade in CTO patients, regardless of Rentrop or Werner classifications.