ABDIC regimen in relapsed or refractory Hodgkin's disease: Results of Gulhane Military Medical Academy Haydarpasa Training Hospital
Marmara Medical Journal, cilt.10, sa.3, ss.135-137, 1997 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 10 Sayı: 3
- Basım Tarihi: 1997
- Dergi Adı: Marmara Medical Journal
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.135-137
- Anahtar Kelimeler: ABDIC regimen, Hodgkin's disease
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: The aim of this study is to present the results of ABDIC regimen in patients with relapsed or refractory Hodgkin's disease treated at the Department of Hematology of Gulhane Military Medical Academy Haydarpasa Training Hospital. Methods: Twelve patients with relapsed or refractory Hodgkin's disease, who had been heavily pretreated, received Doxorubicine, Bleomycin, Dacarbazine, CCNU and Prednisone (ABDIC) regimen. There were 10 men, 2 women and mean age was 31. Results: Complete response was achieved in one patient and 5 patients had partial response. Total response rate was 50% The patient who achieved complete response with ABDIC is alive and free of disease at 13 months. High dose chemotherapy with stem cell transplantation was performed in two patients with partial response and these patients are alive and free of disease at 6 and 11 months respectively. Remaining three partial responders died at 8, 10 and 13 months respectively. Conclusion: ABDIC regimen is a well tolerated and effective regimen for relapsed or refractory Hodgkin's disease patients who received MOPP and ABVD regimen before.