Structure and function of the central retina in red green color vision deficiency: An OCT and Mf-ERG study
Retina-Vitreus, cilt.26, sa.1, ss.34-39, 2017 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 26 Sayı: 1
- Basım Tarihi: 2017
- Dergi Adı: Retina-Vitreus
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.34-39
- Anahtar Kelimeler: Color vision deficiency, Macula, Multifocal electroretinography, Optical coherence tomography
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: This study was designed to investigate whether the structure and electrical potential of the central retina in subjects with red-green color vision deficiency (RG-CVD) differ from normals, or not. Methods: Thirty-four male adults with RG-CVD and 34 age-matched male trichromat controls were enrolled. They had full vision and no systemic and ocular diasase except refractive errors within ±3 diopters. In addition to complete ophthalmic exam, they underwent central foveal thickness (CFT) and retinal nerve fiber layer (RNFL, overall global and 4 quadrants) thickness measurements by optical coherence tomography (OCT, Spectralis®, Heidelberg), and multifocal electroretinography (mf-ERG, Retiscan®, Roland). Results in the groups were compared. Five chronic smokers were excluded from the RG-CVD group. Results: The mean age was 21.51 ± 2.30 years in RG-GVD group and 22.17 ± 2 in controls (p=0.248). CFT and RNFL measurements were similar in both eyes of subjects in both groups (p > 0.05 for all). Remarkably, though not all were statistically significant, amplitudes of both N1 and P1 were higher and latencies of both N1 and P1 were shorter in all hexagons in RG-CVD cases, except for the lower P1 and N1 amplitudes found in the most peripheral one. Conclusion: Subjects with RG-CVD seem to have normal microstructure, but higher electrical potentials with faster activity in the central retina.