Relationship between right atrial pressure and the Model for End-Stage Liver Disease (MELD) score in patients with advanced heart failure İleri evre kalp yetmezliği hastalarında sağ atriyum basıncı ile Son Dönem Karaciğer Hastalığı Modeli (MELD) skoru arasındaki ilişkinin değerlendirilmesi
Turkish Journal of Thoracic and Cardiovascular Surgery, cilt.30, sa.1, ss.1-7, 2022 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 1
- Basım Tarihi: 2022
- Doi Numarası: 10.5606/tgkdc.dergisi.2022.22254
- Dergi Adı: Turkish Journal of Thoracic and Cardiovascular Surgery
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.1-7
- Anahtar Kelimeler: Advanced heart failure, Model for End-Stage Liver Disease Score, right atrial pressure
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: This study aims to investigate the association between right atrial pressure and the Model for End-Stage Liver Diseasescore and to evaluate the ability of this scoring system to accuratelypredict the value of right atrial pressure.Methods: Between April 2016 and November 2018, a total of 137patients (118 males, 19 females; median age: 49 years; range, 40 to54 years) with advanced heart failure who were candidates for leftventricular assist device implantation or heart transplantation wereretrospectively analyzed. We developed a formula calculated by usingthe biochemical and cardiac catheterization parameters of the patients.Results: There was a strong correlation between the right atrialpressure and the scores (r=0.510, p<0.001). The estimated rightatrial pressure was calculated as “2 + (0.92 ¥ Model for End-StageLiver Disease Score)” (unstandardized coefficient 0.920, t value7.674, p<0.001). The Model for End-Stage Liver Disease score wasfound to be an independent predictor of high right atrial pressure(odds ratio=1.491, 95% confidence interval: 1.244-1.786, p<0.001).The calculated area under the curve was 0.789 (95% confidenceinterval: 0.710-0.867, p<0.001) and the cut-off value of the Model forEnd-Stage Liver Disease score in the prediction of high right atrialpressure was 10.5 with 75% sensitivity and 73% specificity.Conclusion: We define a method to calculate right atrial pressureobtained by using the Model for End-Stage Liver Disease scorewithout the need for cardiac catheterization during the hospitalizationand follow-up period of patients with advanced heart failure