Factors affecting drug compliance and incompliance in ankylosing spondyilitis patients Ankilozan spondilitli hastalarda i̇laç uyumunu ve uyumsuzluǧunu etkileyen faktörler


GÜRÇAY E., Ekşioglu E., Yüzer S., BAL A., Çakci A.

Turkiye Fiziksel Tip ve Rehabilitasyon Dergisi, cilt.52, sa.4, ss.163-167, 2006 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52 Sayı: 4
  • Basım Tarihi: 2006
  • Dergi Adı: Turkiye Fiziksel Tip ve Rehabilitasyon Dergisi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.163-167
  • Anahtar Kelimeler: Ankylosing spondylitis, Drug compliance, Medical treatment
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: Ankylosing spondylitis (AS) is a progressive inflammatory disorder of uncertain etiology that mainly affects the axial skeleton. Drug compliance is very important in the treatment of chronic diseases such as AS. This study was carried out to calculate drug compliance rates and to determine the factors that may affect drug compliance in patients with AS. Materials and Methods: Sixty-five outpatients who fulfilled the modified New York criteria for AS were prospectively examined in the study. Compliance to drug treatment was evaluated by interview in terms of adherence to the dose and timing of the prescribed drug regimen. The reasons for compliance and incompliance, detailed drug history and concomitant diseases were asked. Results: Compliance rates for non-steroid anti-inflammatory drugs (NSAID), steroids, and disease modifying antirheumatic drugs (DMARD) were determined as 53%, 67%, and 60-100% of patients, respectively. The most frequent reasons for compliance were "giving adequate information by the doctors", "fear of exacerbation" and "lessening" symptoms. The most frequent reasons for non-compliance were "gastrointestinal complaints", "idea of damaging organs" and "forgetfulness". This study showed that patients with AS were compliant to DMARDs, steroids but less-compliant to NSAIDs. Conclusion: Information about AS and its treatment provided by doctors can play a key role in enhancing drug compliance.