A very rare case - Hairy cell leukemia in patient with sarcoidosis

KARADURMUŞ, Nuri; Erdem, G.; Basaran, Y.; Naharci, I.; TAŞÇI, Cantürk; Dogan, T.; Ifran, A.; Kaptan, K.; SAĞLAM, Kenan; Beyan, C.

doi:10.14735/amko2015215

A very rare case - Hairy cell leukemia in patient with sarcoidosis

KARADURMUŞ N., Erdem G., Basaran Y., Naharci I., TAŞÇI C., Dogan T., ...Daha Fazla

Klinicka Onkologie, cilt.28, sa.3, ss.215-217, 2015 (Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 28 Sayı: 3
Basım Tarihi: 2015
Doi Numarası: 10.14735/amko2015215
Dergi Adı: Klinicka Onkologie
Derginin Tarandığı İndeksler: Scopus
Sayfa Sayıları: ss.215-217
Anahtar Kelimeler: Hairy cell leukemia, Massive splenomegaly, Sarcoidosis
Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Although the coexistence of hairy cell leukemia with sarcoidosis has been reported in a few cases in the literature, in our case the patient had been diagnosed and followed about 10 years with sarcoidosis and massive splenomegaly. It has been demonstrated that T helper 1 cells exist in organs influenced by sarcoidosis. These cells produce IL-2 and IFN-y and induce a nonspecific inflammatory response and granuloma formation. Also these cytokines may play a role in the development of hairy cell leukemia.