Angioedema after intravitreal bevacizumab injection
Cutaneous and Ocular Toxicology, cilt.31, sa.1, ss.85-86, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 1
- Basım Tarihi: 2012
- Doi Numarası: 10.3109/15569527.2011.609207
- Dergi Adı: Cutaneous and Ocular Toxicology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.85-86
- Anahtar Kelimeler: Intravitreal, bevacizumab, systemic hypersensitivity reaction
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
A 47-year-old male with a history of diabetes mellitus type 2 exhibited with decreased vision in both eyes. The diagnosis of cystoid macular edema (CME) was made and it was decided to administer bilateral intravitreal bevacizumab (Avastin) injections. After intravitreal bevacizumab injection (1.25mg/0.05 cc) to the right eye the patient had angioedema and conjunctival chemosis in the right eye which resolved in 48h. One month later the left eye received intravitreal bevacizumab injection under the same conditions. Thirty minutes after the injection angioedema and conjunctival chemosis occurred in the left eye in which the signs and symptoms improved in 48h. This report is the first one which describes angioedema after intravitreal bevacizumab injection. Care should be taken against the systemic hypersensitivity reactions when planned to receive intravitreal bevacizumab injection. © 2012 Informa Healthcare USA, Inc.