Cerebral vein thrombosis in a four year old with Behçet's disease
Reumatologia Clinica, cilt.10, sa.4, ss.254-256, 2014 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 10 Sayı: 4
- Basım Tarihi: 2014
- Doi Numarası: 10.1016/j.reuma.2013.05.007
- Dergi Adı: Reumatologia Clinica
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.254-256
- Anahtar Kelimeler: Behcet's disease, Children, Infliximab, Thrombosis
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Behçet's disease (BD) is a multisystem disorder. The main pathology in BD is vasculitis that involves arteries and veins of all calibers. Central nervous system involvement occurs in 5-10% of patients. Increased morbidity and mortality is rarely observed in children. The mean age at onset in pediatric BD is approximately 7 years. Neurologic involvement in BD is usually observed after 3-6 years. We report the case of a four-year-old Turkish boy with BD with sagittal sinus thrombosis treated with infliximab. The patient presented papilledema without neurologic signs. Although long-term efficacy evaluations are needed in this case, infliximab therapy may be a good option in childhood BD with refractory sinus thrombosis. This is the youngest case of BD with sagittal sinus thrombosis reported so far. © 2012 Elsevier España, S.L.