EASIX as a new predictor of mortality in cerebrovascular diseases
Laboratory Medicine, cilt.57, sa.2, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 57 Sayı: 2
- Basım Tarihi: 2026
- Doi Numarası: 10.1093/labmed/lmaf082
- Dergi Adı: Laboratory Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest)
- Anahtar Kelimeler: EASIX, stroke, mortality, cerebrovascular disease
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction: Cerebrovascular disease (CVD) represents a major global health concern that affects the blood vessels throughout the body and contributes to a considerable burden of mortality and morbidity. The Endothelial Activation and Stress Index (EASIX) has recently emerged as a promising biomarker for predicting many disease complications and outcomes. We aimed to investigate the relationship between EASIX and disease mortality in patients with CVD. Methods: The present study was conducted in a tertiary emergency department between January 6, 2023, and January 6, 2024, who were diagnosed with CVD. The mortality rate among patients within a 1-month period was analyzed. The EASIX was calculated using lactate dehydrogenase level (U/L) × creatinine level (mg/dL)/platelet count (×109/L). The parameters were then compared in relation to disease morbidity. Results: Following the exclusion of patients who met the preestablished exclusion criteria, the study included 74 participants. In the 1-month follow-up of 64 patients, no mortality was observed. The median EASIX score was 0.80 (IQR, 0.5-2.2) in the surviving patients, while the median EASIX score was 2.90 (IQR, 1.00-10.55) in the patients who died, indicating a statistically significantly higher score (P<.001). Discussion: EASIX has the potential to be a prognostic marker for mortality in patients with CVD.