Evaluation of routine four-quadrant re-excision in patients undergoing breast-conserving surgery
Revista da Associacao Medica Brasileira, cilt.72, sa.5, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 72 Sayı: 5
- Basım Tarihi: 2026
- Doi Numarası: 10.1590/1806-9282.20252235
- Dergi Adı: Revista da Associacao Medica Brasileira
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Anahtar Kelimeler: Breast-conserving surgery, Re-excision, Local recurrence
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
OBJECTIVE: The aim of this study was to evaluate the contribution of routine four-quadrant re-excision performed during breast-conserving surgery in detecting de novo tumor foci and ensuring negative surgical margins in patients with breast cancer. METHODS: A retrospective analysis was conducted on 44 female patients who underwent breast-conserving surgery between April 2021 and April 2023. In all cases, routine re-excision was performed in the superior, inferior, medial, and lateral quadrants during the same operative session. Based on pathological findings, patients with additional tumor foci in the re-excision specimens were classified as Group 1, while those without were classified as Group 2. RESULTS: The mean age of the patients was 54.2±11.6 years, with an average follow-up period of 21.5±8.3 months. Additional tumor foci were identified in seven patients (15.9%). There were no statistically significant differences between the groups in terms of age, tumor size, hormone receptor status, or histopathological characteristics (p>0.05). CONCLUSION: Routine four-quadrant re-excision may aid in the identification of microscopic de novo tumor foci even when clear surgical margins are achieved. However, larger multicenter studies with longer follow-up periods are warranted to determine its potential impact on local recurrence and long-term outcomes.