Investigation of the Prevalence of HBV, HCV and HIV in Patients Receiving Hemodialysis Treatment for Chronic Renal Failure Kronik Böbrek Yetmezliği Nedeniyle Hemodiyaliz Tedavisi Uygulanan Hastalarda HBV, HCV ve HIV Sıklığının Araştırılması
Viral Hepatitis Journal, cilt.31, sa.2, ss.36-40, 2025 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 2
- Basım Tarihi: 2025
- Doi Numarası: 10.4274/vhd.galenos.2025.2024-11-1
- Dergi Adı: Viral Hepatitis Journal
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.36-40
- Anahtar Kelimeler: Chronic renal failure, hemodialysis, HBV, HCV, HIV
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objectives: Patients on hemodialysis (HD) are more vulnerable to infections than the general population due to immunosuppression caused by chronic renal failure. Hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) transmitted by blood are the most important causes of morbidity and mortality in these patients. The aim of this study is to investigate the prevalence of HBV, HCV and HIV in chronic renal failure patients undergoing HD treatment over a four-year period. Materials and Methods: This study analyzed 3,799 patient records of persons receiving HD at Meram Medical Faculty and Konya City Hospitals from April 1, 2020, to December 31, 2023. Serum samples from all patients were analyzed for HB surface antigen (HBsAg), anti-HBs, anti-HCV, and anti-HIV markers. The serological parameters were assessed using the Architect I200 SR (Abbott, USA) or the Cobas 8000 immunoassay analyzer (Roche, Mannheim, Germany). Results: After exclusion of duplicate data, 463 patients were eligible for the study. Of the patients, 52.4% were male, and 47.6% were female. The mean age was 54.5±16.1 years. All patients tested negative for anti-HIV. Seventeen patients (3.7%) were positive for anti-HCV, 11 patients (2.3%) were positive for HbsAg, and 423 patients (91.9%) were positive for anti-HBs. Conclusion: Our results regarding the seroprevalence of HbsAg, anti-HCV, and anti-HIV in HD patients were consistent with existing literature from Türkiye. Conversely, we observed an elevated prevalence of anti-HBs positivity among HD patients. The vaccination procedures administered to dialysis patients receiving treatment in tertiary hospitals in Konya were deemed highly effective. We emphasize that those at risk for HBV infection must receive vaccination without exception, and that infection control protocols in dialysis units should adhere to established guidelines.