Assessment of the biointeractivity of a novel vital pulp therapy agent derived from eggshell biowaste: An in vitro study
Australian Endodontic Journal, cilt.50, sa.1, ss.78-88, 2024 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50 Sayı: 1
- Basım Tarihi: 2024
- Doi Numarası: 10.1111/aej.12809
- Dergi Adı: Australian Endodontic Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.78-88
- Anahtar Kelimeler: antibacterial activity, Ca2+ ion-releasing, dentinogenesis, eggshell biowaste, novel dental materials, paediatric dentistry, pulp capping
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
This study aimed to assess the calcium (Ca2+) and hydroxyl (OH−) ion-releasing ability, namely the biointeractivity of eggshell-derived hydroxyapatite (ESDHA) in comparison with mineral trioxide aggregate (MTA) and calcium hydroxide (CH). ESDHA, MTA and CH samples (n = 10; 8 × 1.6 mm) were immersed in 10 mL of deionised water (37°C, pH 6.8). Ca2+ and OH− ion releases were detected in 1, 7 and 21 days. Scanning electron microscopy and Fourier transform infrared spectroscopy analyses were also conducted. IBM SPSS 20.0 was used for statistical analyses. The cumulative Ca2+ ions (56.22 ± 11.28 ppm) were detected as most significant in ESDHA (day 21; p < 0.05). The OH− ion values of the ESDHA group were statistically higher than MTA and CH (days 1 and 7; p < 0.05). ESDHA and CH showed a similar pattern with sharp peaks in Ca2+, oxygen and carbon elements. ESDHA being a sustainable material with a high ion-releasing ability may be a preferable alternative to the commercial vital pulp therapy agents.