Pro-BNP Levels and Its Prognostic Role in Chronic Hypertensive Pregnancies: A Prospective Case-Control Study From A Tertiary Care Hospital
Hypertension in Pregnancy, cilt.40, sa.3, ss.202-208, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 40 Sayı: 3
- Basım Tarihi: 2021
- Doi Numarası: 10.1080/10641955.2021.1939712
- Dergi Adı: Hypertension in Pregnancy
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.202-208
- Anahtar Kelimeler: NT-proBNP, chronic hypertension, pregnancy, perinatal outcome
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: This study aimed to investigate the prognostic value of N-terminal B-type natriuretic peptide (NT-proBNP) in pregnancies with isolated chronic hypertension (HT). Method: 34 pregnant women with chronic HT and 40normotensive controls were enrolled. The association between plasma NT-proBNP levels obtained in the first trimester and perinatal complications were evaluated. Results: NT-proBNP levelsstrongly predicted low birth weight (AUC=0.842, p<0.001). NT-proBNP and birth weight were negatively correlated (r= -0.323, p=0.005). NT-proBNP was found to be an individual determinant of low birth weight in univariate analysis (OR:1.03; 95%CI:1.01-1.04). Conclusion: NT-proBNP levels can be useful to predict low birth weight in pregnancies with chronic HT.