Spectral domain optical coherence tomography findings in carotid artery disease


ÇAKIR A., Düzgün E., DEMİR S., Çakır Y., Ünal M. H.

Turkish Journal of Ophthalmology, cilt.47, sa.6, ss.326-330, 2017 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/tjo.84565
  • Dergi Adı: Turkish Journal of Ophthalmology
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.326-330
  • Anahtar Kelimeler: Carotid artery disease, optical coherence tomography, retinal nerve fiber layer
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objectives: To evaluate the effect of carotid artery disease on retinal morphology by means of spectral domain optical coherence tomography (SD-OCT). Materials and Methods: We examined 23 eyes with internal carotid artery (ICA) stenosis and 24 age- and gender-matched healthy eyes as a control group in this prospective, case-control study. Compherensive ophthalmic examination and SD-OCT scan were performed to all the patients. The average RNFL and macular thicknesses (MT) in the nine macular ETDRS areas were the major OCT measurements for our study. Results: Although all of the average RNFL and MT measurements were lower in the ICA stenosis group, only the total MT and outer ETDRS area (temporal/superior/nasal/inferior outer macula) values were found to be significantly thinner compared to the control group (p=0.004, p=0.009, p<0.001, p=0.002, and p=0.001, respectively). Conclusion: In addition to our knowledge about the effects of ICA stenosis on the retino-choroidal circulation, we found that OCT measurements may be beneficial in the early detection of ocular damage due to ICA stenosis.