Duration of renal failure as risk factor for conjunctival squamous metaplasia
Acta Cytologica, cilt.52, sa.3, ss.309-312, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 52 Sayı: 3
- Basım Tarihi: 2008
- Doi Numarası: 10.1159/000325512
- Dergi Adı: Acta Cytologica
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.309-312
- Anahtar Kelimeler: conjunctiva, impression, cytology, renal failure
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: To assess ocular surface changes in patients with chronic renal failure (CRF), to compare the results with the duration of illness. Study Design: Impression cytology from 48 patients with CRF on regular hemodialysis and 16 age- and sex-matched control subjects were studied. Specimens were taken from the temporal bulbar conjunctiva using cellulose acetate filter paper. Results: Among the patients with CRF who were ill for 0-10 years, 25 patients (78.1%) disclosed grade 0-1, and 7 patients (21.9%) disclosed grade 2-3 cytologic changes, whereas in those with the duration of CRF > 10 years, 9 patients (56.2%) had grade 0-1 and 7 patients (43.8%) had grade 2-3 changes. Specimens from the control group revealed 93.8% grade 0-1 and 6.2% grade 2-3 changes (p < 0.05). Conclusion: The ocular surfaces of patients with CRF differ significantly from those of normal individuals, and the severity of conjunctival changes is related to the duration of CRF. © The International Academy of Cytology.