Ertapenem neurotoxicity in patients with kidney damage: A case report
Acta Facultatis Medicae Naissensis, cilt.38, sa.3, ss.299-304, 2021 (ESCI, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 38 Sayı: 3
- Basım Tarihi: 2021
- Doi Numarası: 10.5937/afmnai38-31596
- Dergi Adı: Acta Facultatis Medicae Naissensis
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, Directory of Open Access Journals
- Sayfa Sayıları: ss.299-304
- Anahtar Kelimeler: ertapenem, seizures, kidney injury
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Ertapenem, a member of the carbapenem group of antibiotics, is a broad-spectrum antibiotic that is effective against multidrug-resistant gram-positive and gram-negative infections. In patients with acute or chronic kidney damage, one of the most serious side effects of ertapenem is neurotoxicity. Various clinical conditions such as seizures, hallucinations, delirium, confusion, and nystagmus may occur. Previous history of cerebral pathologies is a known risk factor for ertapenem-associated neurotoxicity. Immediate discontinuation of treatment is required. Although the symptoms usually resolve rapidly, cases with longer duration of symptoms have also been reported. Close monitoring of neurological status in such patients is essential.