Relation between serum total bilirubin levels and severity of coronary artery disease in patients with non-ST-segment elevation myocardial infarction
Angiology, cilt.65, sa.3, ss.245-249, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 65 Sayı: 3
- Basım Tarihi: 2014
- Doi Numarası: 10.1177/0003319713504820
- Dergi Adı: Angiology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.245-249
- Anahtar Kelimeler: non-ST-segment elevation myocardial infarction, SYNTAX score, bilirubin, coronary artery disease
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
We studied 403 consecutive patients with non-ST-segment elevation myocardial infarction (NSTEMI). This population was divided into tertiles according to the SYNTAX score (SXscore). The high SXscore group was defined as an SXscore ≥13, and the low SXscore group as an SXscore <13. The total bilirubin (sTB) and direct bilirubin levels of patients were significantly higher in the high SXscore group (P =.001 and P =.007, respectively). There was a correlation between sTB and SXscore (r =.495; P =.005). On multivariate linear regression analyses, age (β =.100; P =.041), sTB levels (β =.171; P =.005), low-density lipoprotein cholesterol (β =.121; P =.014), and troponin-I (β =.124; P =.011) remained independent correlates of high SXscore. The mean follow-up period was 18.2 months. All-cause mortality rate was higher in the high SXscore group but did not reach significance (P =.058). In conclusion, high sTB level is independently associated with severity of coronary artery disease in patients with NSTEMI. However, no association was found with long-term mortality. © The Author(s) 2013.