Association between atherogenic dyslipidemia and fournier's gangrene

AKAN S., Urkmez A.

Revista da Associacao Medica Brasileira, cilt.66, sa.4, ss.479-484, 2020 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1590/1806-9282.66.4.479
  • Dergi Adı: Revista da Associacao Medica Brasileira
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.479-484
  • Anahtar Kelimeler: Fasciitis, Hypertriglyceridemia, Genitalia, Fournier gangrene, Genital diseases, male
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: We aimed to determine whether atherogenic dyslipidemia is associated with the disease and morbidity in our patients treated for Fournier's gangrene (FG). Methods: Sixty-two patients who were treated with the diagnosis of FG at our center between 2012 and 2017 were retrospectively screened. Results: The triglyceride values of the patients who required reconstructive surgery were statistically significantly higher than those of the patients for whom wound debridement and primary suturing was sufficient (p:0.001). A total of 65.7% of the patients had normal triglyceride values in the group in which wound debridement and primary suturing was sufficient, while this rate was 22.2% in the group of patients who needed reconstructive surgery; the difference was statistically significant (p: 0.002). The UFGSI score of those with triglyceride values higher than the normal range was statistically significantly higher (p:0.006). The cut-off point for the triglyceride value for which Fournier's gangrene was more morbid and the probability of reconstructive surgery need was significantly higher, i.e., >233mg. Conclusion: Our study has demonstrated that atherogenic dyslipidemia, especially hypertriglyceridemia, is an important factor affecting morbidity and associated with high patient care costs after hospitalization and discharge in FG.