Thyroid functions after contrast agent administration for coronary angiography: A prospective observational study in euthyroid patients Koroner anjiyografi amacıyla kontrast madde verildikten sonra tiroid fonksiyonları: Ötiroid hastalarda prospektif bir gözlemsel çalışma
Anadolu Kardiyoloji Dergisi, cilt.13, sa.4, ss.363-369, 2013 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 4
- Basım Tarihi: 2013
- Doi Numarası: 10.5152/akd.2013.134
- Dergi Adı: Anadolu Kardiyoloji Dergisi
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.363-369
- Anahtar Kelimeler: Contrast media, function tests, thyroid, coronary angiography
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: This study aims to investigate long-term effects of iodinated radiographic contrast media used for coronary angiography (CAG) on the thyroid function in euthyroid patients. Methods: In a prospective observational cohort study, nonionic iodinated contrast material was electively used in 101 patients for coronary angiography. The patients were recruited without age restrictions and, at baseline, all had normal levels of free triiodothyronine (FT3), free thyroxine (FT4) and thyrotropin (TSH). The morphology of the thyroid was evaluated by thyroid ultrasonography (USG). Four and eight weeks after CAG, serum TSH, FT3 and FT4 levels were assessed. Results: Compared to a mean baseline level of 1.49 (25%-75%, range 13-2.21), follow-up TSH levels decreased significantly to 1.45 (25%-75%, range 1.98-0.92, p=0.017) and 1.40 (25%-75%, range 1.89-0.87, p=0.003) at 4 weeks and 8 weeks, respectively (p=0.008). No significant diffe-rence was observed in TSH levels between the 4th and 8th weeks (p=0.833). Conclusion: Iodinated radiographic contrast agents may cause subclinical hyperthyroidism in euthyroid patients undergoing CAG. © 2013 by AVES Yayincilik Ltd.