Changes in Schlemm’s canal morphology after trabeculectomy in open angle glaucoma assessed using anterior segment optical coherence tomography
Clinical and Experimental Optometry, cilt.108, sa.6, ss.694-699, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 108 Sayı: 6
- Basım Tarihi: 2025
- Doi Numarası: 10.1080/08164622.2024.2400319
- Dergi Adı: Clinical and Experimental Optometry
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, MEDLINE
- Sayfa Sayıları: ss.694-699
- Anahtar Kelimeler: Anterior segment optical coherence tomography, aqueous outflow, glaucoma, Schlemm's canal, trabeculectomy
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Clinical relevance: Determining how Schlemm’s canal is affected by trabeculectomy may become a marker for evaluating and monitoring surgical success. Background: This study aims to evaluate the morphological changes in Schlemm’s canal after trabeculectomy using anterior segment optical coherence tomography (AS-OCT). Methods: Thirty-five eyes of 35 patients who were followed up for open-angle glaucoma and indicated for trabeculectomy were included in the study. AS-OCT was performed preoperatively and at week 1, month 1 and month 3 postoperatively. The coronal and meridional diameters of Schlemm’s canal were measured in the temporal and nasal quadrants via AS-OCT. Results: The meridional diameter length of Schlemm’s canal was higher in the nasal quadrant than in the temporal quadrant. Nasally, the mean preoperative meridional diameter length was 326.8 ± 88.5 μm, which increased at postoperative week 1 and month 1. Temporally, it was 271.5 ± 91.5 μm and showed a non-significant change postoperatively. The mean preoperative coronal diameter length was 10.9 ± 6.5 μm and 11.9 ± 6.0 μm in the nasal and temporal quadrants, respectively. A statistically significant increase was found in the measurements of the nasal quadrant at week 1 (p = 0.005) and month 1 (p = 0.049), and in the temporal quadrant at week 1 (p = 0.023). Conclusion: A significant enlargement of the canal occurs at the first postoperative week, followed by a gradual reduction thereafter. The increase in size is mostly observed in the coronal diameters, resulting in the expansion of the canal.