Quantitative evaluation of progression of retinal vascularization after 60 weeks postmenstrual age in infants treated with bevacizumab
Ophthalmic Surgery Lasers and Imaging Retina, cilt.54, sa.7, ss.417-424, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 54 Sayı: 7
- Basım Tarihi: 2023
- Doi Numarası: 10.3928/23258160-20230626-01
- Dergi Adı: Ophthalmic Surgery Lasers and Imaging Retina
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, MEDLINE
- Sayfa Sayıları: ss.417-424
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
BACKGROUND AND OBJECTIVE: To investigate the progression of retinal vascularization after 60 weeks postmenstrual age (PMA) in eyes treated with intravitreal bevacizumab (IVB). PATIENTS AND METHODS: Twenty-seven eyes that were treated with IVB and underwent two consecutive fl uorescein angiographies (FA) after 60 weeks PMA. Horizontal disc diameter (DD), disc-To-fovea (DF) distance, and length of temporal retinal vascularization (LTRV) were measured in pixels on the two consecutive angiograms. RESULTS: Mean age at fi rst and fi nal FA sessions were 77.7 ± 15.7 and 168.0 ± 49.0 weeks PMA, respectively. The DF/DD ratio was 3.30 ± 0.46 and 3.16 ± 0.46 in the fi rst and fi nal FAs (P = 0.001), respectively. The LTRV/DD ratio was 13.38 ± 2.12 and 13.15 ± 2.13 in the fi rst and fi nal FAs (P = 0.027), respectively. The LTRV/DF ratio was 4.06 ± 0.39 and 4.17 ± 0.42, respectively (P = 0.032). CONCLUSION: Temporal retinal vascularization did not progress despite an average follow-up of 90 weeks in pixel units and DD.