Soluble CD40 ligand levels in patients with hypertension


Sonmez A., Dogru T., Yilmaz M., ÖÇAL R., ÖZGÜRTAŞ T., Kilic S., ...Daha Fazla

Clinical and Experimental Hypertension, cilt.27, sa.8, ss.629-634, 2005 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 8
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1080/10641960500298673
  • Dergi Adı: Clinical and Experimental Hypertension
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.629-634
  • Anahtar Kelimeler: hypertension, soluble CD40 ligand
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

CD40 ligand interaction with its receptor (CD40) not only mediates lymphocyte communication, but also associates with chronic inflammation and atherothrombosis. High soluble CD40L (sCD40L) levels were reported in dyslipidemia, diabetes mellitus, and coronary disease. So far, there are no data about sCD40L levels in hypertension. We investigated sCD40L and high sensitive C reactive protein (hsCRP) levels in 30 nonobese young hypertensive men and 30 matched controls. sCD40L and hsCRP levels were not different, and there were no correlations between blood pressure and sCD40L or hsCRP levels. These results might indicate lack of any inflammatory state in new onset hypertension. Copyright © Taylor & Francis, Inc.