Clinical features and comorbidities in psoriatic arthritis Psöriatik artritte klinik özellikler ve eşlik eden hastaliklar
Journal of Rheumatology and Medical Rehabilitation, cilt.18, sa.3, ss.86-89, 2007 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 18 Sayı: 3
- Basım Tarihi: 2007
- Dergi Adı: Journal of Rheumatology and Medical Rehabilitation
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.86-89
- Anahtar Kelimeler: Clinical features, Comorbidity, Psoriatic arthritis
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Psoriatic arthritis (PsA) is a chronic inflammatory disease, usually seronegative, associated with psoriasis. It can affect musculoskeletal system and skin but eyes, kidneys, heart and lungs can be affected, too. The aim of this study was to assess the clinical and laboratory features of patients with PsA and to determine the presence of comorbidities. Materials and Methods: Thirty-two patients who satisfied the diagnostic criteria for PsA according to American College of Rheumatology were included in me study. Clinical subgroups were defined and systemic comorbidities were asked. Complete blood count, levels of ferritin and vitamin B12, presence of antinuclear antibody (ANA) and HLAB27 were examined in laboratory measurements. Results: The mean age of patients was 46.2±12.0 years, median duration of psoriasis and PsA were 17.5 years (range, 2-59 years) and 9.5 years (range, 0.5-55.5 years), respectively. Clinical subgroups of PsA were as follows: asymmetric oligoarthritis in 3.1%, symmetric polyarthritis in 81.3%, and spondylitis in 15.6%. When comorbidities were analyzed, it was observed that 3 patients had pulmonary disease, 4 had heart disease, 11 had hypertension, 6 had diabetes mellitus, 8 had thyroid dysfunction, 6 had gastrointestinal disease, 1 had renal disease, 20 had hyperlipidemia, and 14 had osteoporosis. In laboratory parameters, the incidence of anemia was 53.2%, deficiency in vitamin B12 was 9.4%, and deficiency in ferritin was 21.9%. ANA was found in 7 (21.9%) and HLA B27 was found in 8 (25%) of the patients. There was no difference between the different kinds of anemias and disease duration (p>0.05). Conclusion: Although PsA is a disease affecting the skin and the musculoskeletal system, it is also associated with the increased risk of metabolic disorders and different kinds of anemias so that physicians should be careful during the follow-up. Copyright © 2007 by Türk Tibbi Rehabilitasyon Kurumu Derneǧi.