Vitamin D levels and their relationship with the type of involvement in alopecia areata patients
Journal of Pakistan Association of Dermatologists, cilt.34, sa.1, ss.200-207, 2024 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 34 Sayı: 1
- Basım Tarihi: 2024
- Dergi Adı: Journal of Pakistan Association of Dermatologists
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.200-207
- Anahtar Kelimeler: 25(OH)D3, Alopecia areata, Vitamin D
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background Alopecia areata is an autoimmune dermatosis characterized by non-scarring loss of hair, especially hair, beard, eyebrows and eyelashes. In this case-control study, we investigated the relationship between vitamin D levels and the disease and the type of involvement (patchy, diffuse, total and universal). Methods Forty one non-pregnant and over 18 years of age alopecia areata patients, who applied to the dermatology outpatient clinic of our hospital between 08.03.2016 and 31.05.2016 and who gave informed consent after being given verbal and written information about the study, were included in the study. The control group included 41 non-pregnant people over the age of 18 who applied to the outpatient clinic with complaints other than alopecia areata, matched with the patient group in terms of gender and age. Results There was no statistically significant difference in vitamin D levels between the control and patient groups, as well as between groups separated according to the type of involvement (p=0.06 and 0.72, respectively). There was no significant difference between the 2 groups with normal and low (<30ng/ml) vitamin D in terms of both disease and extent patterns (p=0.11 and 0.37, respectively).When all participants were divided into 3 groups in terms of vitamin D levels: normal, borderline low (20-29.9 ng/ml) and low (<20ng/ml), no statistically significant difference was found in terms of disease and extent patterns (p=0.17 and 0.33, respectively). Conclusion In our study, no statistically significant connection was found between the disease and the extent of involvement in terms of mean vitamin D levels and low vitamin D levels.