Atypical femoral shaft fractures secondary to long-term bisphosphonate therapy
Journal of Orthopaedics, cilt.14, sa.2, ss.226-230, 2017 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 14 Sayı: 2
- Basım Tarihi: 2017
- Doi Numarası: 10.1016/j.jor.2017.01.002
- Dergi Adı: Journal of Orthopaedics
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.226-230
- Anahtar Kelimeler: Atypical femoral fracture, Bisphosohonate, Femoral shaft fracture, Adverse effects, Stress reaction
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background Bisphosphonates (BPs) are one of the most commonly used agents in the treatment of post-menopausal osteoporosis and other metabolic bone diseases. Methods Between 2010 and 2015, data of 22 osteoporotic women with femoral fractures due to low-energy trauma who received BPs previously were analysed. Results The mean duration of BP therapy was 7.6 years. The mean duration of union was 7.4 months. Five patients had non-union. Stress reaction was observed in the contralateral femur in 11 patients. Conclusion Radiographic studies should be performed on a regular basis to prevent atypical femoral fractures in patients on long-term BP therapy.