Do Calcium and Potassium Levels Influence Ductal Patency in Preterm Infants?
American Journal of Perinatology, cilt.37, sa.11, ss.1123-1129, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 37 Sayı: 11
- Basım Tarihi: 2020
- Doi Numarası: 10.1055/s-0039-1692389
- Dergi Adı: American Journal of Perinatology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.1123-1129
- Anahtar Kelimeler: serum potassium, ionized calcium, patent ductus arteriosus, infants, premature, very low birth weight
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective âWe investigated the relationship of serum potassium (K +) and ionized calcium (iCa 2+) levels with the persistence of ductus arteriosus. Study Design âThis retrospective cohort study included infants with birth weight < 1,500 g and gestational age < 32 weeks. Serum K +and iCa 2+levels at the 1st and 48th hour of life were measured from samples. The difference between the two levels was calculated for both serum K +(ΔK +) and iCa 2+(ΔCa 2+). These values were compared between hemodynamically significant patent ductus arteriosus (hsPDA) and non-hsPDA. Results âOf 1,322 hospitalized preterm nonates, 1,196 were included in the study. Mean serum K +levels at the 1st and 48th hour were higher and iCa 2+levels at the 1st and 48th hour were lower in hsPDA and non-hsPDA, respectively (p < 0.001). Ionized ΔCa 2+(-0.06 ± 0.13 vs.-0.02 ± 0.12 mmol/L) was higher in hsPDA (p < 0.001). Conclusion âWe demonstrated that serum K +and iCa 2+level might play a role in ductal constriction.