The incidence of pseudocholinesterase deficiency and contributing factors in pediatric patients in Turkey Turkye'de pedyatrk hastalarda psodokolnesteraz eksklgi ve katkida bulunan faktorlerin Insdansi
Anestezi Dergisi, cilt.26, sa.3, ss.159-163, 2018 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 26 Sayı: 3
- Basım Tarihi: 2018
- Dergi Adı: Anestezi Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.159-163
- Anahtar Kelimeler: Cholinesterase, Hepatic failure, Pseudocholinesterase, Renal failure
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: It is aimed to reveal the frequency of pseudocholinesterase (PCE) deficiency, which is highly important for the possible complications observed during the general anaesthesia applications. Method: The records of patients (age, sex, serum PCE effect levels, liver and kidney functions) were computerized and studied on the data. Results: PCE level in 5.5% of the patients (n=15.309) were under the normal values. The PCE deficiency percentage was high with high alanine amino transferase, aspartate amino transferase, ure and creatinin levels (p<0.001). The patients whose ALT, AST, ure and creatinin level were high as a whole, PCE deficiency percentage was 50% (p<0.001). Conclusion: PCE deficiency is a widespread situation. It is probable to think about the occurrence of the PCE deficiency in case of the increased values especially in the liver and/or kidney functions during the preoperative run in the child patient group.